Detalhe da pesquisa
1.
Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond.
Immunol Rev
; 313(1): 46-59, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36097870
2.
Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis.
J Immunol
; 212(8): 1334-1344, 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38391367
3.
Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMß2.
J Biol Chem
; 298(8): 102168, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35738398
4.
Structural Investigations of Human A2M Identify a Hollow Native Conformation That Underlies Its Distinctive Protease-Trapping Mechanism.
Mol Cell Proteomics
; 20: 100090, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33964423
5.
Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4.
J Immunol
; 204(5): 1345-1361, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31969389
6.
Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes.
Biochemistry
; 59(51): 4799-4809, 2020 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33301305
7.
Complement activation by human IgG antibodies to galactose-α-1,3-galactose.
Immunology
; 161(1): 66-79, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32583419
8.
The lufaxin inhibitor caught in the act.
Blood
; 141(25): 3017-3018, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37347503
9.
Recent cryogenic electron microscopy structures of human A2M may not be representative of the native protein.
Proc Natl Acad Sci U S A
; 119(37): e2210218119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35972981
10.
Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.
RNA
; 23(7): 1110-1124, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28416566
11.
Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J Biol Chem
; 292(39): 16014-16023, 2017 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28801462
12.
Structural Basis for Eculizumab-Mediated Inhibition of the Complement Terminal Pathway.
J Immunol
; 197(1): 337-44, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27194791
13.
Structure of the haptoglobin-haemoglobin complex.
Nature
; 489(7416): 456-9, 2012 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922649
14.
Crystal structure of human S100A8 in complex with zinc and calcium.
BMC Struct Biol
; 16(1): 8, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27251136
15.
Structural and functional characterization of human and murine C5a anaphylatoxins.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 6): 1704-17, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24914981
16.
Filtration and tubular handling of EWE-hC3Nb1, a complement inhibitor nanobody, in wild type mice and a mouse model of proteinuric kidney disease.
FEBS Open Bio
; 14(2): 322-330, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38124617
17.
Chemical Zymogens and Transmembrane Activation of Transcription in Synthetic Cells.
Adv Mater
; 36(6): e2309385, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38009384
18.
Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration.
Mol Immunol
; 165: 29-41, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38142486
19.
Mimer: an automated spreadsheet-based crystallization screening system.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 69(Pt 7): 815-20, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23832216
20.
Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins.
Proc Natl Acad Sci U S A
; 107(24): 10884-9, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20534494